A cyclopropanol-based strategy for subunit coupling: Total synthesis of (+)-spirolaxine methyl ether

A cyclopropanol-based strategy for subunit coupling: Total synthesis of (+)-spirolaxine methyl ether
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DOI:
10.1021/ol0710111
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发表时间:
2007-07-05
期刊:
影响因子:
5.2
通讯作者:
Phillips, Andrew J.
Phillips, Andrew J.
中科院分区:
化学1区
文献类型:
--
作者:
Keaton, Katie A.;Phillips, Andrew J.

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介绍了一种以环丙醇为中间体合成酮的方法及其在(+)-螺烷甲醚中的应用。该合成还具有Fu的烷基-烷基铃木偶联的应用。
A strategy for ketone synthesis with cyclopropanols as intermediates and its application to (+)-spirolaxine methyl ether is described. The synthesis also features an application of Fu's alkyl-alkyl Suzuki coupling.