Intermittent Control Strategy for Stabilizing Human Quiet Stance, A Model of the
Intermittent Control Strategy for Stabilizing Human Quiet Stance, A Model of the
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稳定人类安静姿态的间歇控制策略，一个模型
DOI：
10.1007/978-1-0716-1006-0_100698
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Morasso Pietro G.
中科院分区：
文献类型：
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作者：
Nomura Taishin;Suzuki Yasuyuki;Morasso Pietro G.
简介使用组织学方法进行分析的生物标本必须稳定或保存，以便在整个数据采集阶段都能保持结构关系。生物标本来自活的生物体，标本可以包括整个有机体，如昆虫(如果蝇或果蝇)、线虫(如线虫)或胚胎(如小鼠或斑马鱼胚胎)，也可以是整个中枢神经系统(CNS，包括大脑和脊髓)，取自生物如小鼠、大鼠或成年斑马鱼的大脑。最后，样本还可以包括从包括人脑或脊髓在内的较大生物体中提取的部分中枢神经系统。计算神经解剖学的高通量3D分析实际上仍然局限于对不超过1立方厘米(1.0 cm3)的标本的分析，立方厘米(1.0 cm3)大约是成年小鼠大脑的大小。在本描述中，我们将重点介绍不大于1.0 cm~3的组织样品的制备，并且我们将描述可用于高通量3D分析的样品制备。
Introduction Biological specimens to be analyzed using histological methods must be stabilized or preserved so that structural relationships can be maintained throughout the data acquisition phase. Biological specimens are obtained from living organisms, and specimens can consist of the entire organism such as insects (ie, Drosophila or fruit flies), nematodes (ie, C. elegans), or embryos (ie, mouse or zebra fish embryos), or specimens can be the whole central nervous system (CNS, which includes the brain and spinal cord) taken from organisms such as mouse, rat, or adult zebra fish brain. Finally, samples also can include parts of the CNS taken from larger organisms including the human brain or spinal cord. High-throughput 3D analysis for computational neuroanatomy is still practically limited to analysis of specimens that are not much larger than a cubic centimeter (1.0 cm3), which is the approximate size of an adult mouse brain. For this description, we will focus on the preparation of tissue samples that are no larger than 1.0 cm3, and we will describe specimen preparation that can be used for highthroughput 3D analysis.