High Priority Research Needs for Gestational Diabetes Mellitus
High Priority Research Needs for Gestational Diabetes Mellitus
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DOI：
10.1089/jwh.2011.3270
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发表时间：
2012-09-01
影响因子：
3.5
通讯作者：
Nicholson, Wanda K.
中科院分区：
文献类型：
--
作者：
Bennett, Wendy L.;Robinson, Karen A.;Nicholson, Wanda K.
目的：识别未回答的研究问题，妊娠期糖尿病（GDM）的管理是必要的，集中未来的研究工作。我们开发了一个过程，阐明GDM.Methods的最高优先级的研究问题：使用GDM作为起点的系统评价，我们开发了一个八步的过程：（1）确定研究差距，（2）来自综述作者的反馈，（3）使用人口、干预、比较、结果、环境（PICOS）框架将差距转化为可研究的问题，（4）地方机构利益相关者对研究问题的细化，（5）国家利益相关者使用德尔菲法对研究问题的重要性达成共识，（6）结果的优先级，（7）概念框架，（8）评价。研究问题集中在GDM的药物管理（例如，各种口服药物与胰岛素），GDM妇女的分娩管理（例如，诱导与期待管理），并确定风险因素，预防和筛查2型糖尿病的妇女与先前的GDM。利益相关者评价的发展，慢性疾病的后代，剖腹产，产伤作为高优先级的结果，以衡量在未来的study.Conclusions：我们开发了一个八步的过程中使用一个多学科的利益相关者群体，以确定15个研究问题的高临床重要性。研究人员，政策制定者和资助者可以使用此列表将研究工作和资源用于最优先的领域，以改善对GDM女性的护理。
Objective: Identification of unanswered research questions about the management of gestational diabetes mellitus (GDM) is necessary to focus future research endeavors. We developed a process for elucidating the highest priority research questions on GDM.Methods: Using a systematic review on GDM as a starting point, we developed an eight-step process: (1) identification of research gaps, (2) feedback from the review's authors, (3) translation of gaps into researchable questions using population, intervention, comparators, outcomes, setting (PICOS) framework, (4) local institutions' stakeholders' refinement of research questions, (5) national stakeholders' use of Delphi method to develop consensus on the importance of research questions, (6) prioritization of outcomes, (7) conceptual framework, and (8) evaluation.Results: We identified 15 high priority research questions for GDM. The research questions focused on medication management of GDM (e.g., various oral agents vs. insulin), delivery management for women with GDM (e.g., induction vs. expectant management), and identification of risk factors for, prevention of, and screening for type 2 diabetes in women with prior GDM. Stakeholders rated the development of chronic diseases in offspring, cesarean delivery, and birth trauma as high priority outcomes to measure in future studies.Conclusions: We developed an eight-step process using a multidisciplinary group of stakeholders to identify 15 research questions of high clinical importance. Researchers, policymakers, and funders can use this list to direct research efforts and resources to the highest priority areas to improve care for women with GDM.