Isolation of infectious measles virus in measles encephalitis.
Isolation of infectious measles virus in measles encephalitis.
复制标题
麻疹脑炎中传染性麻疹病毒的分离。
DOI：
10.1016/s0140-6736(72)92595-0
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发表时间：
1972
期刊：
影响因子：
168.9
通讯作者：
R. Meyermann
中科院分区：
文献类型：
--
作者：
V. T. Meulen;V. T. Meulen;V. T. Meulen;Y. Käckell;Y. Käckell;Y. Käckell;D. Müller;D. Müller;D. Müller;M. Katz;M. Katz;M. Katz;R. Meyermann;R. Meyermann;R. Meyermann
一名40岁男子在急性麻疹发病后3天出现脑炎。六周后他死了。组织学检查符合晚发型麻疹脑炎。将尸检时获得的新鲜脑组织匀浆直接接种到易感组织培养物中，未产生感染性病毒。然而，将来自该脑组织的细胞与非洲绿色猴肾组织培养物的连续细胞系共培养，产生了一种被鉴定为麻疹的传染性病毒。
A 40-year-old man developed encephalitis 3 days after onset of acute measles. He died 6 weeks later. Histopathological findings were consistent with late type of post-infectious measles encephalitis. Direct inoculation of a homogenate of fresh brain tissue obtained at necropsy into susceptible tissue cultures produced no infectious virus. However, co-cultivation of cells derived from this brain tissue with those of a continuous line of African green monkey kidney tissue culture yielded an infectious virus that was identified as measles.