Strengths and challenges of longitudinal non-human primate neuroimaging.

Strengths and challenges of longitudinal non-human primate neuroimaging.
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DOI:
10.1016/j.neuroimage.2021.118009
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发表时间:
2021-08-01
期刊:
影响因子:
5.7
通讯作者:
Poirier C
Poirier C
中科院分区:
医学1区
文献类型:
--
作者:
Song X;García-Saldivar P;Kindred N;Wang Y;Merchant H;Meguerditchian A;Yang Y;Stein EA;Bradberry CW;Ben Hamed S;Jedema HP;Poirier C

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Strengths and challenges of longitudinal non-human primate MRI are described. Statistical power calculation of longitudinal and cross-sectional designs are provided. The impact of template choice on grey matter estimation is demonstrated. Recommendations for designing and analysing such studies are provided. Longitudinal non-human primate neuroimaging has the potential to greatly enhance our understanding of primate brain structure and function. Here we describe its specific strengths, compared to both cross-sectional non-human primate neuroimaging and longitudinal human neuroimaging, but also its associated challenges. We elaborate on factors guiding the use of different analytical tools, subject-specific versus age-specific templates for analyses, and issues related to statistical power.
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