Statistical Approach for Optoacoustic Image Reconstruction in the Presence of Strong Acoustic Heterogeneities
Statistical Approach for Optoacoustic Image Reconstruction in the Presence of Strong Acoustic Heterogeneities
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DOI：
10.1109/tmi.2010.2081683
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发表时间：
2011-02-01
影响因子：
10.6
通讯作者：
Ntziachristos, Vasilis
中科院分区：
文献类型：
--
作者：
Dean-Ben, X. Luis;Ma, Rui;Ntziachristos, Vasilis
提出了一种减少光声层析成像图像中由于声波的内反射或散射而产生的伪影的方法。它是基于加权的层析成像的贡献，每个探测器的概率，受声失配的信号被测量在该位置。校正方法不需要成像样品的声学或光学性质的先验知识。性能测试与琼脂幻影，包括空气间隙模仿强烈的声学反射，以及与声学异质性成年斑马鱼。与滤波反投影算法重建的原始图像相比，所提出的方法得到的结果显示出明显的伪影减少。该性能与体内小动物成像应用直接相关，所述体内小动物成像应用涉及在存在骨骼、肺和其他高度不匹配的器官的情况下的成像。
A method is presented to reduce artefacts produced in optoacoustic tomography images due to internal reflection or scattering of the acoustic waves. It is based on weighting the tomographic contribution of each detector with the probability that a signal affected by acoustic mismatches is measured at that position. The correction method does not require a priori knowledge of the acoustic or optical properties of the imaged sample. Performance tests were made with agar phantoms that included air gaps for mimicking strong acoustic reflections as well as with an acoustically heterogeneous adult Zebrafish. The results obtained with the method proposed show a clear reduction of the artefacts with respect to the original images reconstructed with filtered back-projection algorithm. This performance is directly related to in vivo small animal imaging applications involving imaging in the presence of bones, lungs, and other highly mismatched organs.