THE TOPOGRAPHY OF VISUAL-EVOKED RESPONSE PROPERTIES ACROSS THE VISUAL-FIELD
THE TOPOGRAPHY OF VISUAL-EVOKED RESPONSE PROPERTIES ACROSS THE VISUAL-FIELD
复制标题
DOI：
10.1016/0013-4694(94)90114-7
复制
发表时间：
1994-01-01
期刊：
影响因子：
--
通讯作者：
CARNEY, T
中科院分区：
文献类型：
--
作者：
BASELER, HA;SUTTER, EE;CARNEY, T
视觉诱发电位（VEP）的亮度和图形反转刺激的整个中央视野中的大量的小区域的衍生。在一项研究中，用由64个等面积贴片组成的刺激阵列测试该场。局部响应分量提取的独立m序列调制的补丁。使用不同的电极放置，比较受试者之间和受试者内部的场地形。在响应特性中观察到的受试者依赖性局部变异性归因于来自两个或更多个视野的皮质表示的贡献以及大体皮质解剖结构中的受试者间变异。第二项研究使用跨越15度视野的56个贴片的亮度调制，缩放以激活V1区中近似相等的皮层区域。这在所有偏心率下产生了许多稳健的信号。比较了双极和双微分（“一维拉普拉斯”）信号。双差分减少了来自远处或分布式源的贡献，增强了附近的电流源活动，并大大提高了许多刺激位置的S/N。高分辨率视野图表明，由于皮质卷积对反应的影响，使用VEP进行临床现场测试是不可行的。然而，数据质量和数量的巨大改善使其成为VEP源定位和识别的有用工具。
Visual evoked potentials (VEPs) to luminance and pattern reversal stimulation were derived for a large number of small areas throughout the central visual field. In one study, the field was tested with a stimulus array consisting of 64 equal-area patches. Local response components were extracted by independent m-sequence modulation of the patches. Field topographies were compared between and within subjects using different electrode placements. The subject-dependent local variability observed in response characteristics is attributed to contributions from two or more cortical representations of the visual field and to inter-subject variations in gross cortical anatomy. The second study used luminance modulation of 56 patches across a 15 degrees field, scaled to activate approximately equal cortical areas in area V1. This produced many robust signals at all eccentricities. Bipolar and double differential (''1-dimensional Laplacian'') signals were compared. The double differencing reduced contributions from distant or distributed sources, enhancing nearby current source activity, and greatly improved S/N for many stimulus locations. The high-resolution visual field maps demonstrated that clinical field testing using the VEP is not feasible because of effects of cortical convolutions on responses. However, the vast improvement in data quality and quantity make it a useful tool for VEP source localization and identification.