Smoking cessation is associated with lower rates of mood/anxiety and alcohol use disorders.

Smoking cessation is associated with lower rates of mood/anxiety and alcohol use disorders.
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DOI:
10.1017/s0033291713003206
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发表时间:
2014-09
影响因子:
6.9
通讯作者:
Bierut, L. J.
Bierut, L. J.
中科院分区:
医学1区
文献类型:
--
作者:
Cavazos-Rehg, P. A.;Breslau, N.;Hatsukami, D.;Krauss, M. J.;Spitznagel, E. L.;Grucza, R. A.;Salyer, P.;Hartz, S. M.;Bierut, L. J.

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伴随戒烟的心理结果尚未得出结论,但积极的结果可能有助于说服戒烟。我们使用的数据来自酒精和相关疾病的纵向国家流行病学研究。采用逻辑回归分析研究第1波每日吸烟者中吸烟减少与第2波成瘾/心理健康障碍状态之间的相关性,并根据第1波关注的诊断状态进行分层。我们使用倾向评分回归调整,调整了第1波和第2波之间吸烟减少程度不同的吸烟者之间基线协变量的差异。在调整了第2波的倾向评分和其他心理健康/成瘾合并症后,在第1波时有当前或终生吸烟史诊断结果的每日吸烟者中,第2波戒烟预测情绪/焦虑障碍的风险降低(aOR 0.6,95% CI 0.4,0.9)和酒精障碍(aOR 0.7,95% CI 0.5,0.99)。在第1波时无关注结局终身史诊断的每日吸烟者中,第2波戒烟预测第2波时药物使用障碍风险降低(OR 0.3,95% CI 0.1,0.9)。我们的数据并不支持戒烟会导致吸烟者患某些精神疾病的风险增加。相反,我们的数据表明,戒烟与情绪/焦虑或酒精使用障碍的风险降低有关,即使是在已有疾病的吸烟者中。
The psychological outcomes that accompany smoking cessation are not yet conclusive but positive outcomes could help to persuade quitting. We use data from the longitudinal National Epidemiological Study of Alcohol and Related Conditions. Logistic regression was used to examine associations between cigarette smoking reduction and Wave 2 status of addiction/mental health disorder among daily smokers at Wave 1, stratified by status of the diagnosis of interest at Wave 1. We adjusted for differences in baseline covariates between smokers with different levels of smoking reduction between Wave 1 and Wave 2 using propensity score regression adjustment. After adjusting for propensity scores and other mental health/addiction comorbidities at Wave 2, among daily smokers who had current or lifetime history diagnosis of the outcome of interest at Wave 1, quitting by Wave 2 predicted a decreased risk of mood/anxiety disorder (aOR 0.6, 95% CI 0.4, 0.9) and alcohol disorder (aOR 0.7, 95% CI 0.5, 0.99) at Wave 2. Among daily smokers with no lifetime history diagnosis of the outcome of interest at Wave 1, quitting smoking by Wave 2 predicted a decreased risk of drug use disorder at Wave 2 aOR 0.3, 95% CI 0.1, 0.9). There is no support in our data for the concern that smoking cessation would result in smokers’ increased risk of some mental disorders. To the contrary, our data suggest that smoking cessation is associated with risk reduction for mood/anxiety or alcohol use disorder, even among smokers who have had a pre-existing disorder.