Abdominal organ motion during inhalation and exhalation breath-holds: pancreatic motion at different lung volumes compared
Abdominal organ motion during inhalation and exhalation breath-holds: pancreatic motion at different lung volumes compared
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DOI：
10.1016/j.radonc.2016.09.012
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发表时间：
2016-11-01
影响因子：
5.7
通讯作者：
Bel, Arjan
中科院分区：
文献类型：
--
作者：
Lens, Eelco;Gurney-Champion, Oliver J.;Bel, Arjan
目的：与通常的假设相反，器官在屏气期间继续运动。我们研究了屏气过程中肺容量对运动幅度的影响以及屏气过程中速度的变化。材料和方法：16名健康受试者在室内空气中进行60秒吸气屏气，肺容量与吸气容量的100%相似，与吸气容量的70%相似，呼气屏气，肺容量近似于吸气容量的30%和0%。在屏气期间，我们获得了时间分辨率为0.6秒的动态单层磁共振图像。我们使用二维图像相关来获得屏气期间的胰腺和胰腺速度和位移。器官运动速度在前上方向最大，在屏气的前10 s最大，在BH 100%、BH 30%和BH 0%时，膈肌运动速度分别为0.41 mm/s、0.29 mm/s、0.16 mm/s和0.15 mm/s，分别在吸气屏气期间器官运动幅度较大（在BH 100%和BH 70%期间，隔膜分别移动9.8和9.0 mm）（BH 30%和BF 0%期间分别为5.6和4.3 mm）。使用呼气屏气而不是吸气屏气，并将照射延迟到呼吸的前10秒后-保持对于腹部肿瘤的照射可能是有利的。(C)2016爱思唯尔爱尔兰有限公司版权所有。
Purpose: Contrary to what is commonly assumed, organs continue to move during breath-holding. We investigated the influence of lung volume on motion magnitude during breath-holding and changes in velocity over the duration of breath-holding.Materials and methods: Sixteen healthy subjects performed 60-second inhalation breath-holds in room air, with lung volumes of similar to 100% and similar to 70% of the inspiratory capacity, and exhalation breath-holds, with lung volumes of similar to 30% and similar to 0% of the inspiratory capacity. During breath-holding, we obtained dynamic single-slice magnetic-resonance images with a time-resolution of 0.6 s. We used 2-dimensional image correlation to obtain the diaphragmatic and pancreatic velocity and displacement during breath-holding.Results: Organ velocity was largest in the inferior-superior direction and was greatest during the first 10 s of breath-holding, with diaphragm velocities of 0.41 mm/s, 0.29 mm/s, 0.16 mm/s and 0.15 mm/s during BH100%, BH30% and BH0%, respectively. Organ motion magnitudes were larger during inhalation breath-holds (diaphragm moved 9.8 and 9.0 mm during BH100% and BH70%, respectively) than during exhalation breath-holds (5.6 and 4.3 mm during BH30% and BF0%, respectively).Conclusion: Using exhalation breath-holds rather than inhalation breath-holds and delaying irradiation until after the first 10 s of breath-holding may be advantageous for irradiation of abdominal tumors. (C) 2016 Elsevier Ireland Ltd. All rights reserved.