PREDICTABILITY OF SKELETAL-MUSCLE TENSION FROM ARCHITECTURAL DETERMINATIONS IN GUINEA-PIG HINDLIMBS
PREDICTABILITY OF SKELETAL-MUSCLE TENSION FROM ARCHITECTURAL DETERMINATIONS IN GUINEA-PIG HINDLIMBS
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DOI：
10.1152/jappl.1984.57.6.1715
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发表时间：
1984-01-01
影响因子：
3.3
通讯作者：
EDGERTON, VR
中科院分区：
文献类型：
--
作者：
POWELL, PL;ROY, RR;EDGERTON, VR
由骨骼肌产生的最大强直张力（Po）由其功能横截面积（CSA）和其比张力（张力/CSA）确定。从26个不同的豚鼠后肢肌肉获取平均纤维长度（标准化为2.2 μ m的肌节长度）、肌肉质量和肌肉内肌纤维的近似羽状角的测量值，并用于计算CSA。假定比张力为22.5 N. cm。cm-2，并用于确定估计PO的每块肌肉的研究。在第二组豚鼠中，测定了11个选定后肢肌肉和肌肉群的原位Po。估计和测量的Po值有很强的线性关系（r = 0.99）的肌肉和肌肉群测试。比目鱼肌是一种均匀的慢收缩肌肉，其比张力为. apprx。15.4 N. cntdot. cm-2（P < 0.01）。22.5N的特定张力值。cm-2似乎是一个合理的值，为所有混合肌肉的研究，在豚鼠后肢，并可用于估计其Po。
The maximum tetanic tension (Po) generated by a skeletal muscle is determined by its functional cross-sectional area (CSA) and its specific tension (tension/CSA). Measurements of average fiber length (normalized to a sarcomere length of 2.2 .mu.m), muscle mass and approximately angle of pinnation of muscle fibers within a muscle were taken from 26 different guinea pig hindlimb muscles and were used to calculate CSA. The specific tension was assumed to be 22.5 N .cntdot. cm-2 and was used to determine the estimated Po of each muscle studied. In a 2nd group of guinea pigs the in situ Po of 11 selected hindlimb muscles and muscle groups were determined. Estimated and measured Po values had a strong linear relationship (r = 0.99) for muscle and muscle groups tested. The specific tension of the soleus, a homogeneously slow-twitch muscle, was .apprx. 15.4 N .cntdot. cm-2 (P < 0.01). A specific tension value of 22.5 N .cntdot. cm-2 appears to be a reasonable value for all mixed muscles studied in the guinea pig hindlimb and can be used to estimate their Po.