Death due to splenic rupture in suppressor cell mycosis fungoides: a case report.
Death due to splenic rupture in suppressor cell mycosis fungoides: a case report.
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抑制性细胞蕈样肉芽肿因脾破裂死亡：病例报告。
DOI：
10.1093/ajcp/82.1.104
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发表时间：
1984
影响因子：
3.5
通讯作者：
Collins,RD
中科院分区：
文献类型：
--
作者：
Bennett,SR;Greer,JP;Stein,RS;Glick,AD;Cousar,JB;Collins,RD
蕈样肉芽肿的情况下，病理性脾破裂导致腹腔内出血和死亡的描述。据我们所知，脾破裂以前没有报道过蕈样肉芽肿的死亡原因。免疫学研究表明，肿瘤细胞是一种抑制性/细胞毒性T细胞。在大多数蕈样肉芽肿或Sézary综合征病例中，肿瘤细胞是辅助/诱导T细胞。该病例临床上非常具有侵袭性，内脏受累突出，提示蕈样肉芽肿可能具有临床多样性和免疫异质性。
A case of mycosis fungoides in which pathologic rupture of the spleen led to intraperitoneal hemorrhage and death is described. To our knowledge, splenic rupture has not been reported previously as a cause of death in mycosis fungoides. Immunologic studies demonstrated that the neoplastic cell was a suppressor/cytotoxic T-cell. In most cases of mycosis fungoides or the Sézary syndrome, the neoplastic cell has been a helper/inducer T-cell. This case was very aggressive clinically with prominent visceral involvement and suggests that mycosis fungoides may be clinically diverse as well as immunologically heterogeneous.