Kidney-targeted naked DNA transfer by retrograde renal vein injection in rats
Kidney-targeted naked DNA transfer by retrograde renal vein injection in rats
复制标题
DOI：
10.1089/10430340252792585
复制
发表时间：
2002-02-01
影响因子：
4.2
通讯作者：
Miyazaki, JI
中科院分区：
文献类型：
--
作者：
Maruyama, H;Higuchi, N;Miyazaki, JI
肾脏靶向基因转移有望彻底改变肾脏疾病的治疗。以前的基因转移方法使用非病毒载体，通过肾动脉、肾盂或输尿管途径给药进入肾小球、肾小管或间质成纤维细胞，导致低水平的
Kidney-targeted gene transfer is expected to revolutionize the treatment of renal diseases. Previous gene transfer methods using nonviral vectors administered via renal arterial, pelvic, or ureteric routes into the glomerulus, tubules, or interstitial fibroblasts have resulted in low-level expression for