Optimum design for production of tryptophan synthetase subunit from recombinant Escherichia coli in a two-stage continuous flow stirred tank reactor (growth and production stage)
Optimum design for production of tryptophan synthetase subunit from recombinant Escherichia coli in a two-stage continuous flow stirred tank reactor (growth and production stage)
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DOI：
10.1016/0923-0467(95)03065-4
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发表时间：
1996-05-01
期刊：
影响因子：
--
通讯作者：
Roesler, WJ
中科院分区：
文献类型：
--
作者：
Baheri, HR;Hill, GA;Roesler, WJ
This paper concerns the design of tryptophan synthetase subunit production from recombinant Escherchia coli that maximizes the overall productivity in two stages of growth and production. The effects of different design parameters (e.g. distribution of feed between stages, fermentation duration and dilution rates) on the dynamic performance of the process have been investigated and later the best designs for specified conversions are calculated. In addition there is a discussion about the behavior of this dynamic chemostat system compared with a steady state process.
