Visualization and Classification of Deeply Seated Collateral Networks in Moyamoya Angiopathy with 7T MRI
Visualization and Classification of Deeply Seated Collateral Networks in Moyamoya Angiopathy with 7T MRI
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DOI：
10.3174/ajnr.a5700
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发表时间：
2018-07-01
影响因子：
3.5
通讯作者：
Wrede, K. H.
中科院分区：
文献类型：
--
作者：
Matsushige, T.;Kraemer, M.;Wrede, K. H.
本研究旨在评价15例患者的形态学模式和使用超高场MRA与传统DSA进行比较的深部侧支循环网络的描绘。在7 T下采集的序列为TOF-MRA，分辨率为0.22 × 0.22 × 0.41 mm（3），MPH，分辨率为0.7 × 0.7 × 0.7 mm（3）。将相关的深侧支络分为2类6条通路。DSA共检出侧支血管网100个，TOF-MRA检出106个，MPPT检出73个。TOF-MRA和DSA对深侧支循环网络的描绘具有可比性。作者证明了良好的描绘6个不同的深层次的侧支网络pathways in Moyamoya angiopathy.Background AND Purpose：侧支网络在Moyamoya angiopathy有一个复杂的血管结构难以理解的常规检查。本研究的目的是评估形态学模式和划定深坐侧支网络使用超高场MRA与传统DSA.MATERIALS和METHODS比较：15例白色烟雾病血管病变进行了调查，在这项前瞻性试验。在7 T下获得的序列是分辨率为0.22 x 0.22 x 0.41 mm（3）的TOF-MRA和分辨率为0.7 x 0.7 x 0.7 mm（3）的MPT。四名评估者在DSA、TOF-MRA和MPTEE的共识阅读中使用轴向源图像和最大强度投影的5分制评价了深位侧支网络的存在和图像质量。通过McNemar检验比较了不同成像方式对深侧支循环网络的描绘，而图像质量采用Wilcoxon符号秩检验进行了比较。DSA共检出侧支血管网100个，TOF-MRA检出106个，MPPT检出73个。TOF-MRA和DSA对深侧支循环网络的描绘具有可比性（P = 0.25）;然而，两者均优于MPDSA（P <0.001）。结论：本研究显示，使用7 T TOF-MRA对白色成人Moyamoya血管病的6种不同深侧支循环网络路径进行了出色的描绘，与DSA相当。
This study aimed to evaluate morphologic patterns and the delineation of deeply seated collateral networks using ultra-high-field MRA in comparison with conventional DSA in 15 patients. Sequences acquired at 7T were TOF-MRA with 0.22 X 0.22 X 0.41 mm(3) resolution and MPRAGE with 0.7 X 0.7 X 0.7 mm(3) resolution. The relevant deeply seated collateral networks were classified into 2 categories and 6 pathways. A total of 100 collateral networks were detected on DSA; 106, on TOF-MRA; and 73, on MPRAGE. Delineation of deeply seated collateral networks was comparable between TOF-MRA and DSA. The authors demonstrate excellent delineation of 6 distinct deeply seated collateral network pathways in Moyamoya angiopathy.BACKGROUND AND PURPOSE: Collateral networks in Moyamoya angiopathy have a complex angioarchitecture difficult to comprehend on conventional examinations. This study aimed to evaluate morphologic patterns and the delineation of deeply seated collateral networks using ultra-high-field MRA in comparison with conventional DSA.MATERIALS AND METHODS: Fifteen white patients with Moyamoya angiopathy were investigated in this prospective trial. Sequences acquired at 7T were TOF-MRA with 0.22 x 0.22 x 0.41 mm(3) resolution and MPRAGE with 0.7 x 0.7 x 0.7 mm(3) resolution. Four raters evaluated the presence of deeply seated collateral networks and image quality in a consensus reading of DSA, TOF-MRA, and MPRAGE using a 5-point scale in axial source images and maximum intensity projections. Delineation of deeply seated collateral networks by different imaging modalities was compared by means of the McNemar test, whereas image quality was compared using the Wilcoxon signed-rank test.RESULTS: The relevant deeply seated collateral networks were classified into 2 categories and 6 pathways. A total of 100 collateral networks were detected on DSA; 106, on TOF-MRA; and 73, on MPRAGE. Delineation of deeply seated collateral networks was comparable between TOF-MRA and DSA (P = .25); however, both were better than MPRAGE (P < .001).CONCLUSIONS: This study demonstrates excellent delineation of 6 distinct deeply seated collateral network pathways in Moyamoya angiopathy in white adults using 7T TOF-MRA, comparable to DSA.