Awareness, Willingness, and Use of Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Washington, DC and Miami-Dade County, FL: National HIV Behavioral Surveillance, 2011 and 2014.
Awareness, Willingness, and Use of Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Washington, DC and Miami-Dade County, FL: National HIV Behavioral Surveillance, 2011 and 2014.
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DOI：
10.1097/qai.0000000000001414
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发表时间：
2017-07-01
期刊：
影响因子：
--
通讯作者：
Kuo I
中科院分区：
文献类型：
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作者：
Patrick R;Forrest D;Cardenas G;Opoku J;Magnus M;Phillips G 2nd;Greenberg A;Metsch L;Kharfen M;LaLota M;Kuo I
尽管口服PrEP对预防艾滋病毒有效，但长期以来对这种新的预防干预措施的认识和接受情况尚未得到充分研究。利用来自两个受艾滋病毒严重影响的城市地区的NHBS数据，我们检查了MSM中每日口服PrEP的意识、使用和意愿，以及随时间推移与口服PrEP意愿相关的因素。来自华盛顿特区和佛罗里达州迈阿密的男男性行为者于2011年和2014年使用基于场地的抽样方法招募。参与者完成了行为调查和艾滋病毒检测。对口服PrEP的认知、使用和使用意愿进行了检查。对2011年和2014年“极有可能”使用PrEP的人口统计学和行为学相关因素进行了评估。从2011年到2014年，这两个城市的PrEP意识都有所提高（DC: 39.1%至73.8%；迈阿密：19.4%至41.2%），但2014年的使用率仍然很低（DC: 7.7%；迈阿密：1.4%）。在华盛顿特区，使用PrEP的可能性随着时间的推移而下降（从61%到48%），但在迈阿密则有所增加（从48%到60%）。在华盛顿特区，少数族裔与极有可能使用PrEP的几率增加有关，而有1或2-5个伴侣的MSM与有6个以上伴侣的MSM相比，极有可能使用PrEP的几率降低。在迈阿密，2011年白人男男性接触者比西班牙裔男男性接触者更有可能使用PrEP，但这一观察结果在2014年被逆转。在使用PrEP的意识、使用和意愿方面的地理差异表明，需要创新的策略来教育男男性行为者这一有效的预防策略。
Despite the effectiveness of oral PrEP for HIV prevention, knowledge and uptake of this new prevention intervention over time has not been fully studied. Using NHBS data from two urban areas highly impacted by HIV, we examined awareness, use, and willingness to use daily oral PrEP and factors associated with willingness to take oral PrEP among MSM over time. MSM from Washington, DC and Miami, FL were recruited in 2011 and 2014 using venue-based sampling. Participants completed behavioral surveys and HIV testing. Awareness, use, and willingness to use oral PrEP were examined. Demographic and behavioral correlates of being “very likely” to use PrEP in 2011 and 2014 were assessed. PrEP awareness increased from 2011 to 2014 in both cities (DC: 39.1% to 73.8%;Miami: 19.4% to 41.2%), but use remained low in 2014 (DC: 7.7%;Miami: 1.4%). Being very likely to use PrEP decreased over time in DC (61% to 48%), but increased in Miami (48% to 60%). In DC, minority race was associated with increased odds of being very likely to use PrEP, while a reduced odds of being very likely to use PrEP was observed for MSM with 1 or 2-5 partners versus having 6+ partners. In Miami, a higher proportion of White versus Hispanic MSM reported being very likely to use PrEP in 2011, but this observation was reversed in 2014. Geographic differences in awareness, use, and willingness to use PrEP indicate that innovative strategies are needed to educate MSM about this effective prevention strategy.