Haematological factors associated with proliferative retinopathy in homozygous sickle cell disease.
Haematological factors associated with proliferative retinopathy in homozygous sickle cell disease.
复制标题
与纯合镰状细胞病增殖性视网膜病相关的血液学因素。
DOI：
10.1136/bjo.65.1.29
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发表时间：
1981
影响因子：
4.1
通讯作者：
G. Serjeant
中科院分区：
文献类型：
--
作者：
R. Hayes;P. Condon;G. Serjeant
对261例纯合子镰状细胞病患者的血液学指标进行了研究，其中29例发展为增生性镰状视网膜病变（PSR）。在考虑了年龄相关的影响后，高Hb （bbb90 g/dl）和低HbF（< 5%）水平的男性患者似乎构成了PSR的高风险群体。这种关系在女性中不明显，与男性组相比，在Hb水平较低和HbF水平较高的患者中观察到PSR。在该样本中，年龄在40岁或以上的患者中有14%发生PSR。
Haematological indices were investigated in 261 patients with homozygous sickle cell disease, 29 of whom had developed proliferative sickle retinopathy (PSR). After allowing for age-related effects, male patients with high Hb (> 9 g/dl) and low HbF (< 5%) levels appeared to constitute a high risk group for PSR. This relationship was not evident in females, PSR being observed in patients with lower Hb and higher HbF levels than in the male group. PSR occurred in 14% of patients aged 40 years or over in this sample.