Prebiotic carbohydrates in human milk and formulas
Prebiotic carbohydrates in human milk and formulas
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DOI：
10.1080/08035320510043493
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发表时间：
2005-10-01
期刊：
影响因子：
3.8
通讯作者：
Moro, GE
中科院分区：
文献类型：
--
作者：
Boehm, G;Stahl, B;Moro, GE
人乳低聚糖作为益生菌的可溶性纤维，在肠道菌群的出生后发育中起着重要的作用。婴儿配方奶粉几乎不含益生素低聚糖。因此，配方奶喂养的婴儿的肠道菌群与母乳喂养的婴儿的肠道菌群显著不同。由于人乳低聚糖的复杂性，有必要使用替代来源的益生菌成分作为婴儿配方奶粉的成分。本文综述了含有90%短链低聚半乳糖和10%长链低聚果糖的益生菌混合物的实验研究和临床研究资料。数据表明，使用这种益生菌混合物，可以刺激双歧杆菌和乳杆菌的生长，降低粪便pH值，并将病原体的存在降低到与母乳喂养婴儿相似的水平。因此，益生素低聚糖，如研究的混合物，为配方奶喂养的婴儿提供了有益的效果。
Human milk oligosaccharides play an important role, as prebiotic soluble fibres, in the postnatal development of the intestnial flora. Infant formulas are virtually free of prebiotic oligosaccharides. As a consequence, formula-fed infants develop an intestinal flora significantly different to the flora of breastfed infants. Due to the complexity of human milk oligosaccharides, it is necessary to use alternative sources of prebiotic ingredients as components of infant formulas. The present review summarizes the data of experimental research and clinical studies with a prebiotic mixture containing 90% short-chain galacto-oligosaccharides and 10% long-chain fructo-oligosacchrides are summarized. The data demonstrate that, with this prebiotic mixture, the growth of bifidobacteria and lactobacilli can be stimulated, the faecal pH can be decreased, and the presence of pathogens can be reduced to levels similar to those of breastfed infants. Thus, prebiotic oligosaccharides such as the studied mixture provide beneficial effects for formula-fed infants.