Multidisciplinary intensive rehabilitation treatment improves sleep quality in Parkinson's disease.
Multidisciplinary intensive rehabilitation treatment improves sleep quality in Parkinson's disease.
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DOI：
10.1186/s40734-015-0020-9
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发表时间：
2015-01-01
期刊：
影响因子：
--
通讯作者：
Ghilardi, Maria F
中科院分区：
文献类型：
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作者：
Frazzitta, Giuseppe;Maestri, Roberto;Ghilardi, Maria F
背景技术背景：睡眠障碍是帕金森病（PD）最常见的非运动症状之一，极大地干扰了日常活动并降低了生活质量。由于副作用和与抗帕金森病药物的相互作用，药物治疗并不令人满意。虽然研究表明，定期运动可以提高睡眠质量在正常老化，有没有明确的证据在PD.METHODS：在一项回顾性研究中，我们确定了是否一个激烈的身体和多学科的运动计划，提高睡眠质量在一个大的PD患者群体。对两组年龄、性别、病程和药物治疗情况相似的PD患者进行两次PD睡眠量表（PDSS）评分，间隔28天。对照组（49例）不接受康复治疗，治疗组（89例）接受为期28 d的多学科强化康复治疗（每天3次，每次1 h，包括心血管热身、放松、肌肉拉伸、平衡和步态训练、改善日常生活能力的作业疗法）。在28天后的复查中，治疗组的PDSS评分和PDRS评分均有所改善（p
BACKGROUND: Sleep disturbances are among the most common non-motor symptoms of Parkinson's disease (PD), greatly interfering with daily activities and diminishing life quality. Pharmacological treatments have not been satisfactory because of side effects and interactions with anti-parkinsonian drugs. While studies have shown that regular exercise improves sleep quality in normal aging, there is no definitive evidence in PD.METHODS: In a retrospective study, we determined whether an intense physical and multidisciplinary exercise program improves sleep quality in a large group of patients with PD. We analyzed the scores of PD Sleep Scale (PDSS), which was administered twice, 28days apart, to two groups of patients with PD of comparable age, gender, disease duration and pharmacological treatment. The control group (49 patients) did not receive rehabilitation, The treated group (89 patients) underwent a 28-day multidisciplinary intensive rehabilitation program (three one-hour daily sessions comprising cardiovascular warm-up, relaxation, muscle-stretching, balance and gait training, occupational therapy to improve daily living activities).RESULTS: At enrolment, control and treated groups had similar UPDRS and PDSS scores. At re-test, 28days later, UPDRS and total PDSS scores improved in the treated (p