Protective efficacy of lambda-cyhalothrin treated nets in Anopheles gambiae pyrethroid resistance areas of Cote d'Ivoire
Protective efficacy of lambda-cyhalothrin treated nets in Anopheles gambiae pyrethroid resistance areas of Cote d'Ivoire
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DOI：
10.4269/ajtmh.2005.73.859
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发表时间：
2005-11-01
影响因子：
3.3
通讯作者：
Carnevale, P
中科院分区：
文献类型：
--
作者：
Henry, MC;Assi, SB;Carnevale, P
在冈比亚按蚊拟除虫菊酯抗药性地区，首次在社区一级评估了经三氟氯氰菊酯（一种拟除虫菊酯杀虫剂）处理的蚊帐对疟疾感染和疾病的效力。这项研究是在科特迪瓦北方进行的，那里是kdr耐药地区。根据人口统计学、社会学和生态学标准，选择了四对村庄进行匹配。在每一组中，随机分配一个村庄接受蚊帐。80%以上的床位覆盖了经高效氯氟氰菊酯处理过的蚊帐，6个月后重新使用。在每个村随机抽取54名0-59个月的儿童，全年进行8个周期7天的临床监测。结果表明，驱虫蚊帐的效力得以维持，无症状疟疾感染率降低了12%，估计对疟疾病的保护效力为56%。
The efficacy of nets treated with lambda-cyhalothrin, a pyrethroid insecticide, on malaria infection and disease was assessed for the first time at the community level in Anopheles gambiae pyrethroid resistance areas. The study was carried out in northern Cote d'Ivoire, which is an area of kdr resistance. Four pairs of villages were selected and matched according to demographic, sociological, and ecological criteria. Among each pair, a village was randomly allocated to receive mosquito nets. More than 80% of beds were covered with nets treated with lambda-cyhalothrin and retreated after 6 months. In each village, 54 children aged 0-59 months were randomly selected and clinically monitored for 8 periods of 7 days throughout the year. Results showed that the efficacy of treated nets was maintained with a reduction of the prevalence of asymptornatic malaria infection by 12% and an estimated protective efficacy against malaria disease of 56%.