Evaluation of subsecond gated helical CT for quantification of coronary artery calcium and comparison with electron beam CT
Evaluation of subsecond gated helical CT for quantification of coronary artery calcium and comparison with electron beam CT
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DOI：
10.2214/ajr.174.4.1740915
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发表时间：
2000-04-01
影响因子：
5
通讯作者：
Burke, GL
中科院分区：
文献类型：
--
作者：
Carr, JJ;Crouse, JR;Burke, GL
目的：自20世纪90年代初引入以来，螺旋CT已成为获得医学应用CT图像的主要技术。本报告结合了螺旋CT时间分辨率（亚秒级）的最新改进和回顾性心脏门控的增加，评价了心脏门控螺旋CT定量冠状动脉钙。我们将亚秒门控螺旋CT测定的总钙分数与目前冠状动脉钙评估的参考值电子束CT进行比较。我们比较了36名68 +/- 11岁（年龄范围，41-85岁）的个体使用通用、未改良螺旋CT扫描仪获得的总钙评分与使用电子束CT获得的评分。相关系数范围为0.97 - 0.98（Pearson积矩）和0.95 - 0.96（斯皮尔曼秩次），取决于所用的冠状动脉钙评分方法。在阈值总钙评分为10、100、160、200、400和680时，参与者被分类为“健康”或“疾病”的一致性为。分别为94%、97%、89%、92%、94%和100%。配备回顾性心脏门控的通用当前一代螺旋CT扫描仪可以准确量化冠状动脉钙，并且结果与电子束CT获得的评分高度相关。作为测量冠状动脉钙的替代方法，门控亚秒心脏螺旋CT提供了更大的可用性和更低的成本，从而使基于人群的冠状动脉钙筛查更加可行。
OBJECTIVE, Since its introduction early in the 1990s, helical CT has become the predominant technology for obtaining CT images for medical applications. Recent improvements in the temporal resolution of helical CT (subsecond) and the addition of retrospective cardiac gating are combined in this report evaluating cardiac-gated helical CT for quantifying coronary artery calcium. We compare total calcium scores determined on subsecond gated helical CT with the current reference for coronary calcium evaluation, electron beam CT.MATERIALS AND METHODS. We compared total calcium scores obtained using a general purpose, unmodified helical CT scanner with scores obtained using electron beam CT in 36 individuals who were 68 +/- 11 years old (age range, 41-85 years).RESULTS. Correlation coefficients ranged from 0.97 to 0.98 (Pearson's product moment) and from 0.95 to 0.96 (Spearman's rank order), depending on the coronary calcium scoring method used. Agreement in the classification of participants as "healthy" or "diseased" at threshold total calcium scores of 10, 100, 160, 200, 400, and 680 was. respectively, 94%, 97%, 89%, 92%, 94%, and 100% using the conventional electron beam CT scoring method and an equivalent method with helical CT.CONCLUSION. A general purpose, current generation helical CT scanner equipped for retrospective cardiac gating can accurately quantify coronary calcium, and the results are highly correlated to scores obtained with electron beam CT. As an alternative method for measuring coronary calcium, gated subsecond cardiac helical CT offers greater availability and lower cost, thereby making population-based screening for coronary artery calcium more feasible.