Changes of gastrointestinal motility evoked by spinal cord cooling and heating
Changes of gastrointestinal motility evoked by spinal cord cooling and heating
复制标题
脊髓冷热引起的胃肠动力变化
DOI：
10.1007/bf00593314
复制
发表时间：
2004
期刊：
影响因子：
--
通讯作者：
S. K. Manchanda
中科院分区：
文献类型：
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作者：
K. Tsuchiya;E. Kozawa;M. Iriki;S. K. Manchanda
在用戊巴比妥钠麻醉的狗中，用气囊法记录胃和十二指肠运动，同时在3-4分钟的持续时间内热刺激脊髓。同时记录动脉血压、呼吸频率、直肠温度、脊髓硬膜外间隙温度和足垫温度。脊髓冷却导致胃和十二指肠收缩波的振幅和紧张水平增加，而脊髓加热则降低振幅和紧张水平。脊髓热刺激引起的胃肠运动变化可能是由自主神经系统介导的，其中至少有消化道交感神经支配的重要贡献，这些结果表明，刺激特定的温度感受性底物引起的胃肠运动变化可能与温度调节和食物摄入之间的密切关系有关。
In dogs anaesthetized with sodium pentobarbital, gastric and duodenal motility were recorded with the balloon method, while the spinal cord was thermally stimulated during periods of 3–4 min duration. Arterial blood pressure, respiratory rate, and the temperatures of the rectum, spinal peridural space and foot pads were recorded simultaneously.Spinal cord cooling resulted in an increase in amplitudes and tonic level of the contraction waves, both in the stomach and in the duodenum, while spinal cord heating decreased amplitudes and tonic level. The changes of gastrointestinal motility evoked by spinal cord thermal stimulation are supposed to be mediated by the autonomic nervous system with an at least significant contribution of the sympathetic innervation of the alimentary canal.These findings suggest that changes of gastrointestinal motility induced by stimulation of specific thermoreceptive substrates might contribute to the close relationship between temperature regulation and food intake.