Preparation of photoreactive derivatives of glutathione and [9-(2-mercaptotryptophan)]corticotropin by selective modification of the sulfhydryl group.
Preparation of photoreactive derivatives of glutathione and [9-(2-mercaptotryptophan)]corticotropin by selective modification of the sulfhydryl group.
复制标题
通过选择性修饰巯基制备谷胱甘肽和[9-(2-巯基色氨酸)]促肾上腺皮质激素的光反应衍生物。
DOI：
10.1021/bi00515a011
复制
发表时间：
1981
期刊：
影响因子：
2.9
通讯作者：
Ramachandran,J
中科院分区：
文献类型：
--
作者：
Muramoto,K;Ramachandran,J
材料和方法按照前面的描述制备高纯度的猪ACTH （Canova-Davis & Ramachandran, 1976）。2,4 - naps - cl和2,5 - naps - cl的合成已有报道（Muramoto & Ramachandran, 1980）。还原谷胱甘肽2,4和2,5 - nap衍生物的制备。加入120毫克（0.40毫摩尔）的
Materials and MethodsHighly purified porcine ACTH was prepared as previously described (Canova-Davis & Ramachandran, 1976). The syntheses of 2, 4-NAPS-Cl and 2, 5-NAPS-Cl have been re-ported previously (Muramoto & Ramachandran, 1980). Preparation of the 2, 4-and2, 5-NAPS Derivatives of Re-duced Glutathione. To a solution of 120 mg (0.40 mmol) of