Interaction of an Asymmetric Scanning Near Field Optical Microscopy Probe with Fluorescent Molecules
Interaction of an Asymmetric Scanning Near Field Optical Microscopy Probe with Fluorescent Molecules
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DOI：
10.2528/pier11091703
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发表时间：
2011
影响因子：
6.7
通讯作者：
Valeria Lotito;U. Sennhauser;C. Hafner;G. Bona
中科院分区：
文献类型：
--
作者：
Valeria Lotito;U. Sennhauser;C. Hafner;G. Bona
本文对基于非对称结构的新型扫描近场光学显微镜探针与单个∞伸缩分子之间的相互作用进行了数值分析。我们的有限元分析表明，这种近场探针可以有效地用于单分子的高分辨率检测，特别是那些具有纵向偶极矩。同时，∞荧光分子可以作为探针顶端近场分布单矢量分量的点状探针，为近场探针表征提供了强有力的工具。
We present a numerical analysis of the interaction between novel scanning near fleld optical microscopy probes based on an asymmetric structure and a single ∞uorescent molecule. Our flnite element analysis shows how such near fleld probes can be efiectively used for high resolution detection of single molecules, in particular those with a longitudinal dipole moment. At the same time, ∞uorescent molecules can be exploited as point-like probes of the single vectorial components of the near fleld distribution at the probe apex, providing a powerful tool for near fleld probe characterization.