Impact of Early Blood Pressure Variability on Stroke Outcomes After Thrombolysis The SAMURAI rt-PA Registry
Impact of Early Blood Pressure Variability on Stroke Outcomes After Thrombolysis The SAMURAI rt-PA Registry
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DOI：
10.1161/strokeaha.112.681007
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发表时间：
2013-03-01
期刊：
影响因子：
8.3
通讯作者：
Toyoda, Kazunori
中科院分区：
文献类型：
--
作者：
Endo, Kaoru;Kario, Kazuomi;Toyoda, Kazunori
背景和目的：本研究确定了静脉溶栓后早期血压变异性与卒中预后的关系。方法：在527名接受阿尔替普酶(0.6 mg/kg)静脉注射的中风患者中，在最初的25小时内测量了8次血压。结果：改良Rankin分级(MRS)0~1级患者的收缩压病程明显低于无改良Rankin分级患者(P
Background and Purpose-The present study determines associations between early blood pressure (BP) variability and stroke outcomes after intravenous thrombolysis.Methods-In 527 stroke patients receiving intravenous alteplase (0.6 mg/kg), BP was measured 8 times within the first 25 hours. BP variability was determined as Delta BP (maximum-minimum), standard deviation (SD), coefficient of variation, and successive variation.Results-The systolic BP course was lower among patients with modified Rankin Scale (mRS) 0 to 1 than those without (P