Cholesterol and cost-effectiveness. Implications for practice, policy, and research.
Cholesterol and cost-effectiveness. Implications for practice, policy, and research.
复制标题
胆固醇和成本效益。
DOI：
10.1161/01.cir.85.5.1939
复制
发表时间：
1992
期刊：
影响因子：
37.8
通讯作者：
Davis,JE
中科院分区：
文献类型：
--
作者：
McBride,PE;Davis,JE
C ardiovascular disease (CVD) care in the United States will cost an estimated $109 billion in 1992.1 Despite the nearly 50% decline in the CVD death rate in the last two decades, approximately one third of the 1.5 million people who will have a myocardial infarction this year will die.'New programs to reduce these societal costs are health care and research priorities. Given the large numbers of individ-uals at risk for CVD and competition for health care resources, clinical policy must consider costs in addition to potential effectiveness. Cost-effectiveness analysis is being used to assess quality and cost implications and to provide policy makers and clinicians with a framework for evaluation of alternative strategies. Cost-effectiveness analysis, as well as meta-analysis, decision analysis, and cost-benefit analysis, provide models for estimating the impact of screening or treat-ing a given condition. 23 Cost-effectiveness analyses provide models for estimating the impact of proposed programs or interventions that may not be easily addressed using traditional clinical research methods. These techniques permit linkages from different sources, includingepidemiology, clinical trials, and cost and outcome studies to address clinical or research questions. Outcome, or effectiveness, is measured with end points such as morbidity, mortality, years of life saved, and estimates of health status and quality of life. 2 Cost-effectiveness studies can also address the incremental effectiveness of given interventions by varying the inputs or assumptions used in the model. In this issue of Circulation, Goldman and colleagues4 present a summary of a conference sponsored by the National Heart, Lung, and Blood Institute National Cholesterol Education Program (NCEP) on the cost and health implications of cholesterol treatment. This landmark report, based on research and expert panel reports, reviews current cost-effectiveness research and the cost implications of cholesterol management under a variety of clinical conditions. This report highlights
