Coq6 hydroxylase: unmasked and bypassed.
Coq6 hydroxylase: unmasked and bypassed.
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Coq6 羟化酶:暴露并被绕过。
DOI:
10.1016/j.chembiol.2011.09.006
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发表时间:
2011
影响因子:
--
通讯作者:
Clarke,CatherineF
中科院分区:
文献类型:
--
作者:
Clarke,CatherineF
Coenzyme Q is a polyisoprenylated benzoquinone lipid essential in cellular energy metabolism. Ozeir et al. (2011) show that an enzyme, Coq6, is required for the coenzyme Q C5-ring hydroxylation, and that defects in Coq6 can be bypassed by providing alternate ring precursors.