Multiple pathways carry signals from short-wavelength-sensitive ('blue') cones to the middle temporal area of the macaque
Multiple pathways carry signals from short-wavelength-sensitive ('blue') cones to the middle temporal area of the macaque
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DOI：
10.1113/jphysiol.2012.241117
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发表时间：
2013-01-01
影响因子：
5.5
通讯作者：
Vidyasagar, Trichur R.
中科院分区：
文献类型：
--
作者：
Jayakumar, Jaikishan;Roy, Sujata;Vidyasagar, Trichur R.
我们记录了单神经元在中颞叶视觉皮层区（MT或V5）的麻醉猕猴穗活动。我们使用闪光，固定的空间限制，锥隔离和亮度调制的刺激均匀的领域，以评估信号的影响，源自长，中，或短（S）波长敏感锥类。近一半（41/86）的MT神经元对S-锥隔离刺激有可靠的反应。进一步测试的神经元中的大多数（19/28）的反应幅度显着降低，但并不总是完全消除，可逆失活的视觉相应区域的同侧初级视觉皮层（纹状皮质，区V1）。因此，目前的数据表明，起源于S-视锥的信号通过V1或通过不经过V1区的路径到达MT区。我们没有发现MT神经元对绕过V1的信号的尖峰反应的平均潜伏期与那些没有的神经元的平均潜伏期之间存在显著差异;我们观察到的相当大的重叠排除了使用尖峰反应潜伏期作为标准来定义信号到达MT的途径。
We recorded spike activity of single neurones in the middle temporal visual cortical area (MT or V5) of anaesthetised macaque monkeys. We used flashing, stationary spatially circumscribed, cone-isolating and luminance-modulated stimuli of uniform fields to assess the effects of signals originating from the long-, medium- or short- (S) wavelength-sensitive cone classes. Nearly half (41/86) of the tested MT neurones responded reliably to S-cone-isolating stimuli. Response amplitude in the majority of the neurones tested further (19/28) was significantly reduced, though not always completely abolished, during reversible inactivation of visuotopically corresponding regions of the ipsilateral primary visual cortex (striate cortex, area V1). Thus, the present data indicate that signals originating in S-cones reach area MT, either via V1 or via a pathway that does not go through area V1. We did not find a significant difference between the mean latencies of spike responses of MT neurones to signals that bypass V1 and those that do not; the considerable overlap we observed precludes the use of spike-response latency as a criterion to define the routes through which the signals reach MT.