Brain-behavior relationships: Evidence from practice effects in spatial stimulus-response compatibility
Brain-behavior relationships: Evidence from practice effects in spatial stimulus-response compatibility
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DOI：
10.1152/jn.1996.76.1.321
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发表时间：
1996-07-01
影响因子：
2.5
通讯作者：
Mazziotta, JC
中科院分区：
文献类型：
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作者：
Iacoboni, M;Woods, RP;Mazziotta, JC
1。我们测量了六个正常受试者的正电子发射断层扫描和（H2O）-O-15的相对脑血流（RCBF）的变化，反复执行空间刺激 - 响应兼容性任务。受试者有两个运动响应条件。他们被指示用左手对左视野光刺激进行响应，右手向右视野光刺激（兼容条件），右手右手到左侧视野光刺激以及左手到右视野光刺激（不兼容条件）。每个受试者对每个条件进行了六次RCBF测量。2。在兼容（287 ms）中的反应时间比不兼容（339 ms）条件（空间刺激 - 响应兼容效应）快（287毫秒）。与兼容的条件相比，在不兼容的条件下观察到了两个半球的上顶叶的RCBF的双侧增加（p <0.05）。未观察到RCBF降低。反应时间与两个活化的上顶叶区域中的RCBF相关（p <0.0001）3。根据线性趋势，反应时间减少了（p <0.05）。在左半球的背侧前额叶，前额叶和原发性运动皮层中观察到与实践相关的线性RCBF增加（p <0.05）。未观察到显着的RCBF降低4。实践不会影响空间刺激响应兼容性效果。在兼容和不兼容的条件下，在左右手反应以及左右视野中都观察到反应时间的平行缩短。因此，当分析RCBF时，实践相互作用的空间刺激反应兼容性并未显示出任何显着的活化区域。5。这些发现表明，左右右顶叶叶中的两个激活区域可用于视觉刺激空间属性到运动响应空间属性上的映射，并且RCBF在不兼容的响应条件下增加了更复杂的计算重新映射。和响应在空间上不匹配6。左半球的背外侧前额叶，前室和运动RCBF线性增加似乎反映了实践对兼容和不兼容响应条件共有的皮质过程的影响。这些皮质过程大概可以增强刺激与不同刺激反应兼容条件下的反应之间的联系。 RCBF增加的横向化表明这些过程中的左半球优势。
1. We measured relative cerebral blood flow (rCBF) changes with positron emission tomography and (H2O)-O-15 in six normal subjects repeatedly performing a spatial stimulus-response compatibility task. Subjects had two motor response conditions. They were instructed to respond with the left hand to a left visual field light stimulus and with the right hand to a right visual field light stimulus (compatible condition), and with the right hand to a left visual field light stimulus and with the left hand to a right visual field light stimulus (incompatible condition). Six rCBF measurements per condition were performed in each subject.2. Reaction times were faster (P < 0.0005) in the compatible (287 ms) than the incompatible (339 ms) condition (spatial stimulus-response compatibility effect). A bilateral increase (P < 0.05) in rCBF in the superior parietal lobule of the two hemispheres was observed during the incompatible condition when compared with the compatible one. No rCBF decreases were observed. Reaction times correlated (P < 0.0001) with the rCBF in the two activated superior parietal lobule areas.3. Reaction times decreased with practice according to a Linear trend (P < 0.05). Practice-related linear rCBF increases (P < 0.05) were observed in the dorsolateral prefrontal, premotor, and primary motor cortex of the left hemisphere. No significant rCBF decreases were observed.4. Practice did not affect the spatial stimulus-response compatibility effect. A parallel shortening of reaction times was observed in both compatible and incompatible conditions, in both left and right hand responses, and in both left and right visual fields. Accordingly, when rCBF was analyzed, the spatial stimulus-response compatibility by practice interaction did not show any significant activated area.5. These findings suggest that the two activated areas in the left and right superior parietal lobules subserve the mapping of the visual stimulus spatial attributes onto the motor response spatial attributes and that the rCBF increases in the incompatible response condition represent the more complex computational remapping required when stimuli and response do not match spatially.6. The dorsolateral prefrontal, premotor, and motor rCBF linear increases in the left hemisphere seem to reflect the effect of practice on cortical processes common to both compatible and incompatible response conditions. These cortical processes presumably strengthen the links between stimuli and responses under different stimulus-response compatibility conditions. The lateralization of the rCBF increases suggests a left hemisphere superiority in these processes.