Malaria dispersal among islands:: human mediated Plasmodium falciparum gene flow in Vanuatu, Melanesia

Malaria dispersal among islands:: human mediated Plasmodium falciparum gene flow in Vanuatu, Melanesia
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DOI:
10.1016/j.actatropica.2003.09.022
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发表时间:
2004-04-01
期刊:
影响因子:
2.7
通讯作者:
Kobayakawa, T
Kobayakawa, T
中科院分区:
医学2区
文献类型:
--
作者:
Lum, JK;Kaneko, A;Kobayakawa, T

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在瓦努阿图的模式岛屿系统中,人类和恶性疟原虫基因流动模式的比较,太平洋疟疾的极限表明,人类的移动是长距离的,但不是短距离的恶性疟原虫基因流动所必需的。这表明,人类的长距离移动可能会加速抗药性的进化和传播,从而加剧全球疟疾问题。(C)2003 Elsevier B.V.保留所有权利。
A comparison of human and Plasmodium falciparum gene flow patterns in the model island system of Vanuatu, the limit of malaria in the Pacific reveals that human movement is essential for long, but not short distance P. falciparum gene flow. This suggests that long distance movement of humans may accelerate the evolution and spread of drug resistance and therefore exacerbate the global malaria problem. (C) 2003 Elsevier B.V. All rights reserved.