Further Investigations on the Promoting Effect of Mesoporous Silica on Base-Catalyzed Aldol Reaction
Further Investigations on the Promoting Effect of Mesoporous Silica on Base-Catalyzed Aldol Reaction
复制标题
DOI：
10.1007/s11244-010-9477-9
复制
发表时间：
2010-04
影响因子：
3.6
通讯作者：
Y. Kubota;H. Yamaguchi;Taku Yamada;S. Inagaki;Y. Sugi;T. Tatsumi
中科院分区：
文献类型：
--
作者：
Y. Kubota;H. Yamaguchi;Taku Yamada;S. Inagaki;Y. Sugi;T. Tatsumi
在有机胺催化的4-硝基苯甲醛与丙酮的羟醛反应混合物中加入有序介孔二氧化硅，显著提高了反应速度，高产率地合成了β-羟基酮。红外光谱分析表明，表面硅醇与胺之间的协同作用可能是提高反应速率的原因。
Addition of an ordered mesoporous silica to a mixture of an aldol reaction, comprising 4-nitrobenzaldehyde with acetone catalyzed by organic amines, caused significant increase in the reaction rate to afford the β-hydroxyketone in high yield. A cooperative effect between the surface silanol and amine was considered to be the likely reason for the rate-enhancement, which was supported by FTIR spectroscopy.