Monocyte functions in diabetes mellitus.
Monocyte functions in diabetes mellitus.
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单核细胞在糖尿病中发挥作用。
DOI：
10.1111/j.1699-0463.1982.tb01414.x
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
K. Kølendorf
中科院分区：
文献类型：
--
作者：
C. Geisler;T. Almdal;J. Bennedsen;J. Rhodes;K. Kølendorf
本研究的目的是研究从14例糖尿病（DM）患者获得的单核细胞的功能，并与来自健康个体的单核细胞进行比较。发现14例糖尿病患者外周血单核细胞总数低于健康人。白念珠菌的吞噬作用在患者的单核细胞中减少，而吖啶的胞饮作用和乳胶和绵羊红细胞的吞噬作用正常。对酪蛋白的趋化反应增强。这些研究结果的可能后果，为阐明合并感染的糖尿病患者进行了讨论。
The aim of this study was to investigate the functions of monocytes obtained from 14 patients with diabetes mellitus (DM) compared with those of monocytes from healthy individuals. It was found that the total number of circulating monocytes in the 14 diabetic patients was lower than that from the healthy individuals. Phagocytosis of Candida albicans was decreased in the monocytes from the patients, whereas pinocytosis of acridine and phagocytosis of latex and sheep red blood cells were normal. The chemotactic response towards casein was enhanced. The possible consequences of these findings for the elucidation of concomitant infections in diabetic patients are discussed.