Antibodies to sporozoites: their frequent occurrence in individuals living in an area of hyperendemic malaria.
Antibodies to sporozoites: their frequent occurrence in individuals living in an area of hyperendemic malaria.
复制标题
子孢子抗体：它们经常出现在生活在高流行性疟疾地区的个体中。
作者：
E. Nardin;R. Nussenzweig;I. McGregor;J. Bryan
对158名西非人的血清样本进行了针对孢子虫抗体的检测，孢子虫是疟疾寄生虫的媒介阶段。采用环孢子子沉淀法和间接免疫荧光法检测恶性疟原虫孢子子特异性抗体。超过90%的成人血清样本对恶性疟原虫孢子虫的免疫荧光反应呈阳性，而大多数儿童样本的免疫荧光反应较低或呈阴性。
Serum samples from 158 West Africans were tested for antibodies against sporozoites, the vector stage of the malaria parasite. Antibodies specific for Plasmodium falciparum sporozoites were detected by means of the circumsporozoite precipitation assay and indirect immunofluorescence. More than 90 percent of the serum samples from adults gave positive immunofluorescent reactions against falciparum sporozoites, whereas most of the samples from children gave low or negative reactions.