Collagen tube conduits in peripheral nerve repair: a retrospective analysis.
Collagen tube conduits in peripheral nerve repair: a retrospective analysis.
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DOI：
10.1007/s11552-009-9245-0
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发表时间：
2010-09-01
期刊：
影响因子：
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通讯作者：
Kalliainen, Loree K
中科院分区：
文献类型：
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作者：
Wangensteen, Kirk J;Kalliainen, Loree K
对2002年至2007年在地区医院接受NeuraGen导管的所有患者进行了图表审查，地区医院是一家I级创伤中心。96例患者使用NeuraGen导管进行了126次修复，并对患者进行了随访。修复主要是上肢感觉神经，但有6个是身体其他部位的神经修复。术中无并发症，但有2例术后轻微并发症和1例术后肺血栓形成。126例修复中有40例失访。在126例修复中，26例进行了神经恢复的定量测试(两点辨别、Semmes-Weinstein或肌电测试)，其中35%报告有改善，31%接受翻修手术。在126例修复中，60例进行了定性测试(主观或客观的感觉或运动功能报告)，45%的修复报告有所改善，5%的修复手术进行了翻修手术。接受翻修手术的患者更有可能接受了感觉的定量评估。总体而言，在我们的经验中，感觉恢复在35%-45%之间。我们的结果表明，NeuraGen胶原蛋白导管可以安全地在全身使用。
A chart review was conducted of all patients receiving NeuraGen conduits from 2002 to 2007 at Regions Hospital, a level I trauma center. Ninety-six patients underwent 126 repairs using NeuraGen conduits, and 64 patients were seen in follow-up. Repairs were largely of upper extremity sensory nerves but six were repairs of nerves elsewhere in the body. There were no intra-operative complications, but there were two minor postoperative complications and one postoperative pulmonary embolus. Forty of 126 repairs were lost to follow-up. Twenty-six of 126 repairs had follow-up with quantitative testing of nerve recovery (2-point discrimination, Semmes-Weinstein, or EMG testing), with 35% reporting improvement and 31% going on to a revision operation. Sixty of 126 repairs had qualitative testing performed (subjective or objective reporting of sensation or motor function), with 45% reporting improvement and 5% going on to a revision operation. Patients who went on to revision surgery were more likely to have undergone quantitative evaluation of sensation. Overall, sensory recovery was in the 35-45% range in our experience. Our results indicate that NeuraGen collagen conduits can be used safely throughout the body.