EVIDENCE FOR ABNORMALITY OF BONE-MATRIX PROTEINS IN OSTEOGENESIS IMPERFECTA
EVIDENCE FOR ABNORMALITY OF BONE-MATRIX PROTEINS IN OSTEOGENESIS IMPERFECTA
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成骨不全症中骨基质蛋白异常的证据
DOI：
10.1016/s0140-6736(75)90173-7
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发表时间：
1975
期刊：
影响因子：
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通讯作者：
A. Veis
中科院分区：
文献类型：
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作者：
I. Dickson;E. Millar;A. Veis
免疫和生化技术证实4例成骨不全患儿骨有机基质非胶原蛋白在数量和组成上均存在异常。这代表了到目前为止在成骨不全症和正常骨之间发现的主要分子差异。
Immunological and biochemical techniques demonstrated that the non-collagenous proteins of the organic matrix of bone were abnormal in quantity and composition in four children with osteogenesis imperfecta. This represents the main molecular difference found so far between bone in osteogenesis imperfecta and normal bone.