THE DETERMINATION OF SALICYLIC ACID IN PLASMA

THE DETERMINATION OF SALICYLIC ACID IN PLASMA
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血浆中水杨酸的测定

DOI:
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发表时间:
1944
期刊:
影响因子:
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通讯作者:
A. Coburn
A. Coburn
中科院分区:
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文献类型:
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作者:
B. Brodie;S. Udenfriend;A. Coburn

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介绍了一种测定血浆中水杨酸的方法。用二氯乙烯从酸性介质中萃取,从血浆中分离水杨酸。然后将其作为有色铁络合物返回到水相并进行比色测定。该方法简单,可在常规治疗剂量下对血浆水杨酸浓度进行常规估计。
A method is described for the estimation of salicylic acid in plasma. The salicylic acid is separated from plasma by extraction with ethylene dichloride from an acid medium. It is then returned as the colored iron complex to an aqueous phase and determined colorimetrically. The procedure is simple and permits the routine estimation of the plasma concentrations of salicylic acid achieved with the usual therapeutic doses.