Relation Between Respiratory Muscle Strength and Skeletal Muscle Mass and Hand Grip Strength in the Healthy Elderly.
Relation Between Respiratory Muscle Strength and Skeletal Muscle Mass and Hand Grip Strength in the Healthy Elderly.
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DOI：
10.5535/arm.2017.41.4.686
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发表时间：
2017-08
期刊：
影响因子：
--
通讯作者：
Son S
中科院分区：
文献类型：
--
作者：
Shin HI;Kim DK;Seo KM;Kang SH;Lee SY;Son S
探讨老年人肌肉减少指数与呼吸肌力的关系。这项研究包括65名60岁以上的志愿者（30名男性和35名女性）。采用生物阻抗法测定骨骼肌质量指数（SMI）。肢体肌肉功能通过握力（HGS）、短期体能成套测验（SPPB）和步态速度进行评估。RMS通过使用肺量计的最大吸气压（MIP）和最大呼气压（MEP）来解决。RMS和其他肌肉减少指数之间的关系进行了研究，使用皮尔逊相关系数和多元回归分析调整的年龄，HGS，和SPPB。MIP和MEP与SMI均呈正相关（r分别为0.451和0.388，P均<0.05）。HGS与MIP和MEP均呈显著相关（r分别为0.560，p<0.01和0.393，p<0.05）。步态速度与MIP或MEP之间无显著相关性。SPPB与MEP呈正相关（r= 0.436，p <0.05）。多元回归分析显示，MIP与HGS和SMI显著相关（分别为p<0.001和p<0.05），而MEP仅与HGS相关（p<0.05）。本研究提示呼吸肌尤其是吸气肌与肢体肌力和骨骼肌质量显著相关。MIP和MEP的临床意义有待于进一步的前瞻性研究。
To evaluate sarcopenic indices in relation to respiratory muscle strength (RMS) in elderly people. This study included 65 volunteers over the age of 60 (30 men and 35 women). The skeletal muscle mass index (SMI) was measured using bioimpedance analysis. Limb muscle function was assessed by handgrip strength (HGS), the Short Physical Performance Battery (SPPB), and gait speed. RMS was addressed by maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) using a spirometer. The relationships between RMS and other sarcopenic indices were investigated using the Pearson correlation coefficients and multiple regression analysis adjusted for age, HGS, and SPPB. Both MIP and MEP were positively correlated with SMI (r=0.451 and r=0.388, respectively, p<0.05 in both). HGS showed a significant correlation with both MIP and MEP (r=0.560, p<0.01 and r=0.393, p<0.05, respectively). There was no significant correlation between gait speed and either MIP or MEP. The SPPB was positively correlated with MEP (r=0.436, p<0.05). In the multiple regression analysis, MIP was significantly associated with HGS and SMI (p<0.001 and p<0.05, respectively), while MEP was related only with HGS (p<0.05). This study suggests that respiratory muscles, especially inspiratory muscles, are significantly related to limb muscle strength and skeletal muscle mass. The clinical significance of MIP and MEP should be further investigated with prospective studies.