Microsatellite analysis of malaria parasites.
Microsatellite analysis of malaria parasites.
复制标题
DOI:
10.1007/978-1-62703-389-3_17
复制
发表时间:
2013-01-01
期刊:
影响因子:
--
通讯作者:
Ferreira, Marcelo U
中科院分区:
文献类型:
--
作者:
Orjuela-Sanchez, Pamela;Brandi, Michelle C;Ferreira, Marcelo U
Microsatellites have been increasingly used to investigate the population structure of malaria parasites, to map genetic loci contributing to phenotypes such as drug resistance and virulence in laboratory crosses and genome-wide association studies and to distinguish between treatment failures and new infections in clinical trials. Here, we provide optimized protocols for genotyping highly polymorphic microsatellites sampled from across the genomes of the human malaria parasites Plasmodium falciparum and P. vivax that have been extensively used in research laboratories worldwide.