Peroxisome Morphology in Pathologies
Peroxisome Morphology in Pathologies
复制标题
病理学中的过氧化物酶体形态
DOI:
10.1007/978-3-7091-1788-0_7
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发表时间:
2014
影响因子:
2
通讯作者:
M. Islinger
中科院分区:
文献类型:
--
作者:
M. Schrader;I. Castro;H. Fahimi;M. Islinger
Peroxisomes are ubiquitous and heterogeneous multi-purpose organelles, which are indispensable for human health and development. The invention of specific cytochemical staining methods for peroxisomes revealed their high plasticity and ability to alter their morphology in response to environmental cues. Peroxisome dynamics depend on peroxisomal morphology proteins such as Pex11p, DLP1/Drp1, Fis1, Mff, and GDAP1 which are partially shared with mitochondria. Here, we address variations of peroxisome morphology in the healthy organism and summarize findings on altered organelle morphology in peroxisomal disorders. We highlight recent insights in novel disorders with defects in peroxisome morphology proteins and alterations of peroxisomes during stress and signaling, as well as secondary alterations in liver disease and cancer.
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DOI:
10.1111/j.1530-0277.2008.00827.x
发表时间:
2009-02
期刊:
ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH
影响因子:
--
作者:
Purohit, Vishnudutt;Gao, Bin;Song, Byoung-Joon
通讯作者:
Song, Byoung-Joon
影响因子:
3.8
作者:
Hiebler S;Masuda T;Hacia JG;Moser AB;Faust PL;Liu A;Chowdhury N;Huang N;Lauer A;Bennett J;Watkins PA;Zack DJ;Braverman NE;Raymond GV;Steinberg SJ
通讯作者:
Steinberg SJ
影响因子:
3.9
作者:
Wightman, PJ;Santer, R;FitzPatrick, DR
通讯作者:
FitzPatrick, DR
影响因子:
6.6
作者:
R. Vasko;Brian B. Ratliff;S. Bohr;E. Nadel;Jun Chen;S. Xavier;P. Chander;M. Goligorsky
通讯作者:
R. Vasko;Brian B. Ratliff;S. Bohr;E. Nadel;Jun Chen;S. Xavier;P. Chander;M. Goligorsky
影响因子:
3.3
作者:
Gandre-Babbe, Shilpa;van der Bliek, Alexander M.
通讯作者:
van der Bliek, Alexander M.