DIFFERENTIAL ADHESION OF PATHOGENIC CANDIDA SPECIES TO EPITHELIAL AND INERT SURFACES
DIFFERENTIAL ADHESION OF PATHOGENIC CANDIDA SPECIES TO EPITHELIAL AND INERT SURFACES
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DOI：
10.1111/j.1574-6968.1985.tb00791.x
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发表时间：
1985-01-01
影响因子：
2.1
通讯作者：
DOUGLAS, LJ
中科院分区：
文献类型：
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作者：
CRITCHLEY, IA;DOUGLAS, LJ
已知在含有500 mM半乳糖的培养基中生长可促进白色念珠菌与颊上皮细胞或丙烯酸的体外粘附。在其它5个种中，只有C.在这些条件下生长后，Tropicalis（一种菌株）显示出对颊细胞（但不对丙烯酸）的粘附显著增加。第二株C. tropicalisas和C. stellatoidea，C.近平滑C. pseudotropicalis、C. Guilliermondii和Saccharomyces gallae对两种表面的粘附力几乎没有或没有增加。然而，在含有50mM葡萄糖的培养基中生长后，C.热带和C. parapsilosisare显着更粘附丙烯酸比葡萄糖生长的酵母菌的其他物种，包括C。白色念珠菌。这些结果进行了讨论，在有关的pathogenicandaspecies的殖民化和感染潜力。
Growth in medium containing 500 mM galactose is known to promote the adhesion ofCandida albicansto buccal epithelial cells or to acrylic in vitro. Of 5 otherCandidaspecies tested, onlyC. tropicalis(one strain) showed substantially increased adhesion to buccal cells (but not to acrylic) after growth under these conditions. A second strain ofC. tropicalisas well asC. stellatoidea, C. parapsilosis, C. pseudotropicalis, C. guilliermondiiandSaccharomyces cerevisiaeshowed little or no increased adhesion to either surface. However, after growth in medium containing 50 mM glucose,C. tropicalisandC. parapsilosiswere significantly more adherent to acrylic than glucose-grown yeasts of the other species, includingC. albicans. These results are discussed in relation to the colonization and infection potential of the pathogenicCandidaspecies.