Cortical hyperostosis following long-term administration of prostaglandin E1 in infants with cyanotic congenital heart disease.
Cortical hyperostosis following long-term administration of prostaglandin E1 in infants with cyanotic congenital heart disease.
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患有紫绀型先天性心脏病的婴儿长期服用前列腺素 E1 后出现皮质骨质增生。
DOI：
10.1016/s0022-3476(80)80282-4
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
T. Iwaya
中科院分区：
文献类型：
--
作者：
K. Ueda;A. Saito;H. Nakano;M. Aoshima;M. Yokota;Ryusuke Muraoka;T. Iwaya
前列腺素E或PGE~的使用受到限制，因为它有发热、腹泻、低血压、呼吸暂停和导管损伤等并发症。[8]然而，最近，长期低剂量给予PGE 1或PGE 2已被证明对具有高手术风险的小婴儿几乎没有明显的副作用。5
DISCUSSIONThe use of PGE, or PGE~ has been limited because of the complications of fever, diarrhea, hypotension, apnea, and damage to the ductus. 8 Recently however, long-term low-dose administration of PGE1 or PGE2 has been shown to have few significant side effects in small infants with high surgical risk?-5