In-home solid fuel use and cardiovascular disease: a cross-sectional analysis of the Shanghai Putuo study.
In-home solid fuel use and cardiovascular disease: a cross-sectional analysis of the Shanghai Putuo study.
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DOI：
10.1186/1476-069x-11-18
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发表时间：
2012-03-28
期刊：
影响因子：
--
通讯作者：
Christiani DC
中科院分区：
文献类型：
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作者：
Lee MS;Hang JQ;Zhang FY;Dai HL;Su L;Christiani DC
尽管最近的研究证据表明，使用煤炭或生物质等固体燃料造成的家庭空气污染与高血压等心血管事件之间存在关联，但关于这种暴露对除高血压以外的心血管终点的影响的流行病学数据很少。我们探讨了家庭固体燃料使用与自我报告的心血管终点诊断之间的关联，例如高血压、冠心病 (CHD)、中风和糖尿病。我们分析了 14,068 名 18 岁及以上的中国成年人。在调整潜在混杂因素后，使用逻辑回归模型估计每个结果风险的比值比 (OR) 和相应的 95% 置信区间 (CI)。调整潜在混杂因素后，家庭使用固体燃料与高血压（OR 1.70，95% CI 1.40 至 2.07）、CHD（OR 2.58，95% CI 1.53 至 4.32）和糖尿病（OR 2.48，95% CI 1.59 至 3.86）风险增加显着相关。与接触固体燃料持续时间最低三分位数的个体相比，接触固体燃料持续时间最高三分位数的个体患高血压（OR 1.73，95% CI 1.45 至 2.06）、中风（OR 1.87，95% CI 1.03 至 3.38）和糖尿病（OR 3.18，95% CI 2.11 至 3.38）的几率增加。 4.78）。我们的数据表明，家庭中接触固体燃料可能与中国成年人患高血压、冠心病、中风和糖尿病的风险增加有关。有必要进行进一步的大规模纵向研究来证实这些发现。
Although recent research evidence suggests an association between household air pollution from solid fuel use, such as coal or biomass, and cardiovascular events such as hypertension, little epidemiologic data are available concerning such exposure effects on cardiovascular endpoints other than hypertension. We explored the association between in-home solid fuel use and self-reported diagnoses of cardiovascular endpoints, such as hypertension, coronary heart disease (CHD), stroke, and diabetes. We analyzed 14,068 Chinese adults, aged 18 years and older. Odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated using logistic regression models for the risk of each outcome after adjusting for potential confounders. The use of solid fuel in home was significantly associated with an increased risk for hypertension (OR 1.70, 95% CI 1.40 to 2.07), CHD (OR 2.58, 95% CI 1.53 to 4.32), and diabetes (OR 2.48, 95% CI 1.59 to 3.86), after adjusting for potential confounders. Compared with individuals in the lowest tertile of the duration of solid fuel exposure, those in the highest tertile of the duration of solid fuel exposure had an increased odds of hypertension (OR 1.73, 95% CI 1.45 to 2.06), stroke (OR 1.87, 95% CI 1.03 to 3.38), and diabetes (OR 3.18, 95% CI 2.11 to 4.78). Our data suggest that in-home solid fuel exposure maybe associated with increased risk for hypertension, CHD, stroke, and diabetes in the Chinese adult population. Further large-scale longitudinal studies are warranted to confirm these findings.