Adenoendocrine Cell Carcinoma of the Gallbladder: Report of a Case

Adenoendocrine Cell Carcinoma of the Gallbladder: Report of a Case
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胆囊腺内分泌细胞癌一例报告

DOI:
10.1007/s00595-006-3249-y
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发表时间:
2006
期刊:
影响因子:
2.5
通讯作者:
N. Inoue
N. Inoue
中科院分区:
医学4区
文献类型:
--
作者:
A. Tsuchiya;Yoshiyuki Endo;T. Yazawa;Atsuko Saito;N. Inoue

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胆囊腺内分泌细胞癌是一种罕见的肿瘤。我们治疗了一位36岁的女性,她来找我们的主诉是腹痛。诊断为胆囊肿瘤样肿块,强烈怀疑为胆囊腺肌瘤病。腹腔镜胆囊切除术成功,组织病理发现为胆囊腺内分泌细胞癌。小圆细胞癌肿瘤细胞突触素、神经元特异性烯醇化酶、cd56部分阳性,腺癌细胞角蛋白阳性,提示腺内分泌细胞癌。治疗12个月后,患者仍然存活,病情良好。
Adenoendocrine cell carcinoma of the gallbladder is an uncommon form of cancer. We treated a 36-year-old woman who came to us with a chief complaint of abdominal pain. The abnormality was diagnosed to be a tumor-like mass in the gallbladder, and adenomyomatosis of the gallbladder was strongly suspected. A laparoscopic cholecystectomy was successfully performed, and the histopathological finding was adenoendocrine cell carcinoma of the gallbladder. The tumor cells of the small round cell carcinoma partly stained positively for synaptophysin, neuron-specific enolase, and CD 56, while adenocarcinoma cells showed positive reactions to keratin, which was thus suggestive of adenoendocrine cell carcinoma. The patient is alive and doing well at 12 months after the treatment.