THE EXTRACELLULAR SPACE IN BRAIN TUMORS PART 1 MORPHOLOGICAL CONSIDERATIONS
THE EXTRACELLULAR SPACE IN BRAIN TUMORS PART 1 MORPHOLOGICAL CONSIDERATIONS
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DOI：
10.1093/brain/93.4.693
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发表时间：
1970-01-01
影响因子：
1.7
通讯作者：
BAKAY L
中科院分区：
文献类型：
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作者：
BAKAY L
结果结果总结在表I中。在所有研究的胶质瘤中，细胞外间隙都扩大（图1，LIT板），但其中一些显示出很大的变化，包括几乎正常的细胞间裂隙区域，测量体积的8%，以及细胞外区室严重扩张的区域（60- 70%）。大多数肿瘤的平均发病率在20%到40%之间，在本报告中胶质母细胞瘤和星形细胞瘤之间没有明显的差异。两个内皮瘤型脑膜瘤显示其细胞外间隙适度增大。这种扩大是由于在几个细胞的连接处存在三角形或菱形的楔形物，而不是由于分隔两个相邻细胞体的裂缝的扩张造成的（图2）。
RESULTS The results are summarized in Table I. The extracellular space was enlarged in all gliomas studied (fig. 1, Plate LIT), but some of them showed great variations, including areas of almost normal intercellular clefts, measuring 8 per cent of volume as well as areas of greatly distended extracellular compartments (60-70 per cent). The average in most of these tumours was between 20 and 40 per cent. There was no appreciable difference in this report between glioblastomas and astrocytomas. The two endotheliomatous meningiomas showed modest enlargement of their extracellular space. This enlargement was caused by the presence of triangular or rhomboid-shaped wedges at the junction of several cells rather than by the distension of the cleft separating two adjacent cell bodies (fig. 2).