A Concise and Modular Synthesis of Pyranicin
A Concise and Modular Synthesis of Pyranicin
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DOI：
10.1021/ol802041c
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发表时间：
2008-11-06
期刊：
影响因子：
5.2
通讯作者：
Phillips, Andrew J.
中科院分区：
文献类型：
--
作者：
Griggs, Nolan D.;Phillips, Andrew J.
报道了含四氢吡喃的番荔枝内酯吡喃菌素的模块式13步合成法。主要特征是使用Achmatowicz氧化-Kishi还原序列用于从呋喃组装吡喃酮和应用Fu的烷基-烷基Suzuki偶联用于亚基工会。
A modular, 13-step synthesis of the tetrahydropyran-containing annonaceous acetogenin pyranicin is reported. Key features are the use of an Achmatowicz oxidation-Kishi reduction sequence for the assembly of a pyranone from a furan and the application of Fu's alkyl-alkyl Suzuki coupling for subunit union.