Cerebral Hemodynamic Responses During Dynamic Posturography: Analysis with a Multichannel Near-Infrared Spectroscopy System.
Cerebral Hemodynamic Responses During Dynamic Posturography: Analysis with a Multichannel Near-Infrared Spectroscopy System.
复制标题
DOI：
10.3389/fnhum.2015.00620
复制
发表时间：
2015
影响因子：
2.9
通讯作者：
Shojaku H
中科院分区：
文献类型：
--
作者：
Takakura H;Nishijo H;Ishikawa A;Shojaku H
为了研究大脑皮质在站立平衡中的作用，在受试者接受感觉组织测试(SOT)方案的同时，使用近红外光谱(NIRS)记录了右半球的皮质血流动力学活动，该方案系统性地扰乱了感觉整合过程(即，躯体感觉或视觉输入或两者兼而有之)。11名健康男性在NIRS记录期间接受了SOT。分组统计分析是基于10个不同感兴趣皮质区域的氧合血红蛋白浓度的变化，并基于NIRS统计参数图的一般线性分析。统计分析表明，在不同条件下，右侧额盖(f-Op)、右侧顶盖(p-Op)、右侧颞上回(STG)、右侧顶后皮质(PPC)、右侧背侧和腹侧运动前皮质(PMC)以及辅助运动区(SMA)均有明显激活。对SOT条件的特定组合的激活模式表明：(1)当站立平衡被扰乱时，f-Op、p-Op和STG是感觉整合所必需的；(2)SMA参与了意志动作的执行和新的运动程序的建立，以维持姿势平衡；(3)PPC和PMC参与了前庭和视觉信息之间感觉冲突的空间参照系的更新和计算。
To investigate cortical roles in standing balance, cortical hemodynamic activity was recorded from the right hemisphere using near-infrared spectroscopy (NIRS) while subjects underwent the sensory organization test (SOT) protocol that systematically disrupts sensory integration processes (i.e., somatosensory or visual inputs or both). Eleven healthy men underwent the SOT during NIRS recording. Group statistical analyses were performed based on changes in oxygenated hemoglobin concentration in 10 different cortical regions of interest and on a general linear analysis with NIRS statistical parametric mapping. The statistical analyses indicated significant activation in the right frontal operculum (f-Op), right parietal operculum (p-Op), and right superior temporal gyrus (STG), right posterior parietal cortex (PPC), right dorsal and ventral premotor cortex (PMC), and the supplementary motor area (SMA) under various conditions. The activation patterns in response to specific combinations of SOT conditions suggested that (1) f-Op, p-Op, and STG are essential for sensory integration when standing balance is perturbed; (2) the SMA is involved in the execution of volitional action and establishment of new motor programs to maintain postural balance; and (3) the PPC and PMC are involved in the updating and computation of spatial reference frames during instances of sensory conflict between vestibular and visual information.