Multi-projection Correlation Imaging as a New Diagnostic Tool for Improved Breast Cancer Detection
Multi-projection Correlation Imaging as a New Diagnostic Tool for Improved Breast Cancer Detection
复制标题
多投影相关成像作为改进乳腺癌检测的新诊断工具
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
T. Mertelmeier
中科院分区：
文献类型：
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作者：
A. Chawla;E. Samei;J. Lo;T. Mertelmeier
Multi-projection imaging technique offers an advantage over single projection imaging techniques in rendering pathology that may be surrounded by a complex cloud of anatomical structures. The process of harnessing the geometrical and statistical dependences between the multiple images available in a multi-projection system to determine the final diagnosis is termed Correlation Imaging (CI). In this study, we are investigating the potential improvement in breast cancer detection via CI. As a key step towards that, the acquisition scheme of CI was first optimized to maximize its diagnostic performance. Toward that end, first a clinically-realistic task was designed and each component of acquisition, namely, the acquisition dose level, the number of projections, and their angular span was systematically changed to determine a specific combination that yielded maximum performance in that task. Finally, the performance of the optimized system was compared with that of standard planar mammography. The results indicated that the performance of CI may potentially be optimized between 15-17 projections spanning an angular arc of 45o. This optimum performance further improved with increasing dose levels; however, at dose level comparable to mammography, CI provided a factor of 1.1 improvement over mammography. The framework developed in this study to evaluate multi-projections system may be applied to any other multi-projection imaging modality, and by including reconstruction, may be extended to digital breast tomosynthesis and breast computed tomography.
DOI：
10.2214/ajr.06.0843
发表时间：
2007
期刊：
AJR. American journal of roentgenology
影响因子：
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作者：
Samei,Ehsan;Stebbins,StantonA;Dobbins3rd,JamesT;McAdams,HPage;Lo,JosephY
通讯作者：
Lo,JosephY