Whole‐body imaging of the distribution of mercury released from dental fillings into monkey tissues
Whole‐body imaging of the distribution of mercury released from dental fillings into monkey tissues
复制标题
从牙齿填充物释放到猴子组织中的汞分布的全身成像
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
F. Lorscheider
中科院分区：
文献类型：
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作者：
L. Hahn;R. Kloiber;R. Leininger;M. Vimy;F. Lorscheider
The fate of mercury (Hg) released from dental “silver” amalgam tooth fillings into human mouth air is uncertain. A previous report about sheep revealed uptake routes and distribution of amalgam Hg among body tissues. The present investigation demonstrates the bodily distribution of amalgam Hg in a monkey whose dentition, diet, feeding regimen, and chewing pattern closely resemble those of humans. When amalgam fillings, which normally contain 50% Hg, are made with a tracer of radioactive 203Hg and then placed into monkey teeth, the isotope appears in high concentration in various organs and tissues within 4 wk. Whole‐body images of the monkey revealed that the highest levels of Hg were located in the kidney, gastrointestinal tract, and jaw. The dental profession's advocacy of silver amalgam as a stable tooth restorative material is not supported by these findings.— Hahn, L. J.; Kloiber, R.; Leininger, R. W.; Vimy, M. J.; Lorscheider, F. L. Whole‐body imaging of the distribution of mercury released from dental fillings into monkey tissues. FASEB J. 4: 3256‐3260; 1990.
