Postpartum glucose testing, related factors and progression to abnormal glucose tolerance in a rural population with a known history of gestational diabetes
Postpartum glucose testing, related factors and progression to abnormal glucose tolerance in a rural population with a known history of gestational diabetes
复制标题
DOI：
10.1016/j.dsx.2017.03.035
复制
发表时间：
2017-11-01
影响因子：
10
通讯作者：
Tahery, Noorollah
中科院分区：
文献类型：
--
作者：
Ghajari, Haydeh;Nouhjah, Sedigheh;Tahery, Noorollah
目的：妊娠期糖尿病是产后发展为葡萄糖耐受不良的一个重要危险因素。本研究的目的是确定合并妊娠期糖尿病的妇女在妊娠后进行产后血糖检测的比率、相关因素和进展为葡萄糖耐受不良的比率。材料：这是一项回顾性研究，纳入了2005-2015年期间在Khuramshahr（伊朗西南部）3个农村卫生中心接受产前护理的妊娠糖尿病妇女。妊娠期糖尿病仅通过FPG检测，75g OGTT或GCT诊断。美国糖尿病协会（ADA）产后葡萄糖耐受不良（糖尿病前期或糖尿病）的定义标准。结果：平均随访29.7个月。孕前和产后分别有73.3%和78.7%的女性BMI >= 25。45.8%（60/131）的妇女接受了产后血糖检测。进展为糖耐量异常的比率为23.3%（糖尿病前期8.5%，糖尿病15.2%）。高龄产妇与产后血糖检测相关（OR 1.066, CI 1.008-1.128, p=0.02）。讨论：超重和肥胖的高发率，产后血糖测试的次优率和葡萄糖耐受不良的高发率，突出了产后筛查更敏感的测试和实施干预计划的重要性，以预防农村人口，特别是有妊娠糖尿病史的老年妇女2型糖尿病。(c) 2017年印度糖尿病。Elsevier Ltd.出版。版权所有。
Aims: Gestational diabetes is a strong risk factor for postpartum progression to glucose intolerance. The aims of the study were to determine rate of postpartum glucose testing, its related factors and rate of progression to glucose intolerance in women who underwent postpartum glucose testing after pregnancy that complicated by gestational diabetes.Materials: this is a retrospective study and women with gestational diabetes who received prenatal care during 2005-2015 in 3 rural health centers of Khuramshahr (southwestern of Iran) were enrolled. Gestational diabetes mellitus diagnosed by FPG test only, 75g OGTT or GCT. The American Diabetes Association(ADA) criteria applied for definition of postpartum glucose intolerance (pre-diabetes or diabetes).Results: Mean duration of follow-up was 29.7 months. BMI >= 25 was detected in 73.3% and 78.7% of women during pre-pregnancy and postpartum respectively. Overall 45.8% (60/131) of women received postpartum glucose testing. Rate of progression to abnormal glucose tolerance was 23.3% (8.5% prediabetes and 15.2% diabetes). Advanced maternal age was associated with postpartum glucose testing (OR 1.066, CI 1.008-1.128, p=0.02).Discussion: high rate of overweight and obesity, sub optimal rate of postpartum glucose testing and high prevalence of glucose intolerance, highlights the importance of postpartum screening with a more sensitive test and implementation of an intervention program to prevent type 2 diabetes in rural population particularly older women with prior gestational diabetes. (c) 2017 Diabetes India. Published by Elsevier Ltd. All rights reserved.