Comparison between homologous human milk supplements and a commercial supplement for very low birth weight infants
Comparison between homologous human milk supplements and a commercial supplement for very low birth weight infants
复制标题
DOI：
10.2223/jped.2166
复制
发表时间：
2012-04-01
影响因子：
3.3
通讯作者：
Vargas, Marcio O. F.
中科院分区：
文献类型：
--
作者：
Thomaz, Débora M. C.;Serafim, Paula O.;Vargas, Marcio O. F.
目的：描述了从人乳中制备两种添加剂（液体和粉末）的方法，并将该组合物与商业添加剂FM 85（R）进行比较。方法：使用40份人乳样品制备液体和粉末补充剂。这两种补充剂都经过了三个制备阶段：撇渣、蒸发和去除乳糖。在这些阶段之后，液体补充剂准备好了，并且粉末需要第四阶段-冻干。向液体和粉末补充剂的每个样品中分别加入80 mL（组I）和100 mL（组II）合并的库存人乳。为了进行比较，将20份100 mL合并样品加入5 g FM 85（R）补充剂（Nestle）中（第III组）。对碳水化合物、蛋白质、脂质、钙、磷、钠、渗透压和卡路里含量进行分析，认为差异显著p <0.05。结果：组I、II和III分别显示以下结果：蛋白质= 1.81、2.38和1.96 g/dL（p < 0.001）;碳水化合物= 6.70、7.25和10.06 g/dL（p = 0.006）;脂肪= 3.75、3.75和3.73 g/dL（p = 0.96）;钙= 36.92、44.75和79.37 mg/dL（p = 0.001）;磷= 20.02、23.28和56.30 mg/dL（p = 0.02）;钠= 14.32、14.40和20.33 mEq/L（p = 0.143）;渗透压摩尔浓度= 391.45、412.47和431.00 mOsmol/kgH（2）O（p = 0.074）;热量= 67.78、72.27和81.65千卡（p = 0.001）。所研究的添加剂与商业添加剂FM 85（R）在某些成分上有很大不同，其成分可能符合或不符合最新推荐的营养素含量。
Objectives: To describe the methodology for the preparation of two additives derived from human milk, liquid and powdered, and to compare this composition with the commercial additive FM85 (R).Methods: For the preparation of the liquid and powdered supplements, 40 samples of human milk were used. Both supplements have been through three preparation phases: skimming, evaporation and lactose removal. After these phases, the liquid supplement is ready, and the powdered requires a fourth phase - lyophilization. To each sample of the liquid and powdered supplements were added, respectively, 80 mL (group I) and 100 mL (group II) of pooled banked human milk. For comparison, 20 samples of 100 mL of the pool were added to 5 g of the FM85 (R) supplement (Nestle) (group III). Analyses of carbohydrates, protein, lipids, calcium, phosphorus, sodium, osmolality and caloric content were performed, considering a significant difference p < 0.05.Results: Groups I, II, and III showed, respectively, the following results: protein = 1.81, 2.38 and 1.96 g/dL (p < 0.001); carbohydrates = 6.70, 7.25 and 10.06 g/dL (p = 0.006); fat = 3.75, 3.75 and 3.73 g/dL (p = 0.96); calcium = 36.92, 44.75 and 79.37 mg/dL (p = 0.001); phosphorus = 20.02, 23.28 and 56.30 mg/dL (p = 0.02); sodium = 14.32, 14.40 and 20.33 mEq/L (p = 0.143); osmolality = 391.45, 412.47 and 431.00 mOsmol/kgH(2)O (p = 0.074); and caloric content = 67.78, 72.27 and 81.65 kcal (p = 0.001).Conclusion: The studied additives differ significantly from the commercial additive FM85 (R) in some of its components, and its composition may or may not meet the quantity of nutrients suggested by the most recent recommendations.