Health-related quality of life among patients with facial acne - assessment of a new acne-specific questionnaire

Health-related quality of life among patients with facial acne - assessment of a new acne-specific questionnaire
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DOI:
10.1046/j.1365-2230.2001.00839.x
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发表时间:
2001-07-01
影响因子:
4.1
通讯作者:
Girman, CJ
Girman, CJ
中科院分区:
医学4区
文献类型:
--
作者:
Martin, AR;Lookingbill, DP;Girman, CJ

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面部痤疮的心理社会影响是公认的,但直到最近,很少有经过验证的仪器存在,适用于临床试验。本研究的目的是评估一种新的痤疮特异性生活质量测量工具痤疮生活质量的测量特征(重复性,与痤疮严重程度的相关性,以及检测痤疮治疗后变化的灵敏度)。我们发现,痤疮生活质量是可靠的,有效的,能够区分不同严重程度组和改善超过16周的标准治疗的差异。使用痤疮生活质量应帮助医生了解面部痤疮对年轻人的影响,并可能有助于评估痤疮临床试验的治疗效果。
The psychosocial effects of facial acne are well accepted but until recently few validated instruments existed which were suitable for use in clinical trials. The aim of this study was to assess measurement characteristics (reproducibility, correlation with acne severity, and sensitivity to detect change after acne therapy) of a new acne-specific quality of life instrument, the Acne-QoL. We found that the Acne-Qol, is reliable, valid and able to distinguish differences across severity groups and improvement over 16 weeks of standard therapy. The use of the Acne-QoL should aid physicians in understanding the impact of facial acne on young adults, and may be useful in assessing therapeutic effects in acne clinical trials.